Anti-NIPP1 Antibody

Raised in rabbit against NIPP1 (Nuclear Inhibitor of Protein Phosphatase 1, also known as PPP1R8), this unconjugated polyclonal antibody from Antibodies.com is supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2. The 50 µl volume is configured for Western blot detection of the endogenous target in human, mouse, and rat samples, supporting studies of PP1-dependent regulation in RNA splicing, transcription, and cell cycle progression.

NIPP1 directs protein phosphatase 1 toward nuclear substrates, including spliceosomal components and transcriptional regulators, so researchers investigating phosphatase holoenzyme assembly or mRNA processing can use this reagent to probe expression by immunoblotting. The polyclonal format recognises multiple epitopes on the target protein, which is useful when characterising full-length NIPP1 alongside any isoforms that may be present in nuclear extracts.

For handling, the antibody vial should be kept refrigerated for routine use; for longer-term storage, freeze the reagent in working aliquots to limit repeated freeze-thaw cycles of the stock. The included sodium azide serves as a preservative, which should be considered if the reagent is ever introduced into azide-sensitive live-cell workflows.