Anti-NIPA Antibody

Raised in rabbit against the human NIPA protein, this unconjugated polyclonal antibody from Antibodies.com recognizes an intracellular regulator implicated in cell cycle progression and E2F-dependent transcription. NIPA, encoded by the ZC3HC1 locus, is a nuclear F-box protein best known for interacting with ALK and for harbouring variants that have repeatedly surfaced in genome-wide association studies of coronary artery disease.

The reagent is supplied as 100 µl of stock and performs cleanly across multiple platforms: Western blot detection of endogenous NIPA bands, immunofluorescence staining of fixed cells, and ELISA-based quantification. Cross-reactivity has been validated against Human, Mouse, Rat, and Monkey samples, giving it broad utility for comparative work in mammalian systems.

As a Primary Antibody reagent, the polyclonal format provides recognition of multiple epitopes on the target, which is advantageous when working with post-translationally modified or variably processed NIPA species. Upon receipt, aliquot to limit freeze-thaw cycles and store refrigerated; for longer-term archiving, keep the solution frozen and protect from light to preserve binding activity.