Anti-Nicotinate phosphoribosyltransferase Antibody

Antibodies.com supplies this Rabbit polyclonal reagent raised against Nicotinate phosphoribosyltransferase, the cytosolic enzyme that converts nicotinic acid to nicotinic acid mononucleotide in the Preiss-Handler NAD+ salvage pathway. The unconjugated antibody is delivered as 100 µg of total protein and is validated for Western blot and immunohistochemistry workflows with Human and Mouse samples.

Studies of NAD+ biosynthesis, tumor metabolic rewiring, and substrate-specific rescue of nicotinamide-depleted cells rely on this reagent to follow NAPRT expression in whole-cell lysates and paraffin-embedded tissue sections. For routine handling, refrigerate the vial upon receipt and aliquot before freezing when the antibody will be consumed across multiple experiments, since repeated freeze-thaw cycles gradually reduce polyclonal titer. The format is a single-use vial of 100 µg, sufficient for several western blot membranes or dozens of immunohistochemistry slides depending on dilution.