Anti-NHLRC1 Antibody

Manufactured by Antibodies.com, this affinity-purified polyclonal reagent is raised in rabbit against a recombinant human NHLRC1 immunogen and is supplied at 1 mg/mL in phosphate-buffered saline (pH 7.4, 150 mM NaCl) containing 0.02% sodium azide and 50% glycerol. The unconjugated IgG antibody is validated for Western blot (WB) and immunofluorescence (IF) applications on human samples, where it specifically detects endogenous levels of total NHLRC1 protein. NHLRC1, also known as EPM2B, Malin, NHL repeat-containing protein 1, or RING-type E3 ubiquitin transferase NHLRC1, is the E3 ubiquitin-protein ligase implicated in Lafora disease, making this reagent useful for investigators studying glycogen metabolism, neurobiology, and ubiquitin ligase function. The antibody is provided as a polyclonal host:rabbit, isotype:IgG, conjugate:unconjugated preparation in a 50 µL volume and should be stored at -20 °C. Purification was carried out by affinity chromatography against the immunogen, and the product ships with a typical lead time of 6 to 9 business days. As listed on the supplier page, the reagent is intended for research use only and is not approved for diagnostic or therapeutic applications.