Anti-NHEJ1 Antibody

Antibodies.com offers this rabbit polyclonal IgG reagent raised against NHEJ1, the XRCC4-Like Factor (XLF/Cernunnos) that functions in DNA double-strand break repair through the classical non-homologous end joining pathway.

The unconjugated antibody is supplied as 200 µl of liquid and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples.

Researchers studying V(D)J recombination, lymphoid development, or the DNA damage response can use it to localize NHEJ1 at damage foci, track expression across tissue panels, or confirm knockout phenotypes in cell line models. Because NHEJ1 partners with XRCC4, Ku70/Ku80, and DNA-PKcs to ligate broken DNA ends, the reagent is useful for probing cernunnos-deficient severe combined immunodeficiency phenotypes as well as general genome stability mechanisms.