Anti-NGFR p75 Antibody

Specific detection of the p75 neurotrophin receptor is provided by this rabbit polyclonal antibody from Antibodies.com. NGFR p75, also known as p75NTR, belongs to the TNF receptor superfamily and binds nerve growth factor as well as BDNF, NT-3, and NT-4, transducing both pro-apoptotic and pro-survival signals through co-receptors such as sortilin.

The unconjugated reagent is supplied at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide, packaged as a 100 µl vial. Validated applications cover western blot, immunohistochemistry, immunocytochemistry, and immunoprecipitation of native complexes, with confirmed reactivity against human, mouse, and rat samples.

The reagent is widely used in studies of Schwann cell biology, dorsal root ganglia neurons, neural crest-derived progenitors, basal forebrain cholinergic populations, and neurotrophin-dependent apoptosis. Aliquot working dilutions, store refrigerated, and limit freeze-thaw cycles to preserve activity. For research use only.