Anti-NFKBIE Antibody

NFKBIE (Nuclear Factor Kappa-B Inhibitor Epsilon, also called IκBε) is a cytoplasmic member of the inhibitor of NF-κB family that retains RelA-containing NF-κB complexes in the cytosol until stimulus-dependent phosphorylation triggers their release and nuclear translocation. Polyclonal rabbit IgG antibodies from Antibodies.com raised against this protein support detection of mouse IκBε in western blot workflows, making the reagent relevant to studies of NF-κB signalling kinetics, inflammatory and innate-immune pathway regulation, and oncogenic contexts in which IκBε abundance or function is altered.

The reagent is supplied unconjugated in a 200 µl volume, giving flexibility to run multiple western blot experiments or to optimise antibody dilutions across different lysate preparations. As a polyclonal host: rabbit, IgG isotype reagent, it binds several epitopes on the target, which tends to give stronger and more tolerant signals against the murine protein in cell lysates and tissue homogenates than many monoclonal alternatives. Intended for research use only, the antibody should be stored refrigerated between uses to preserve activity through repeated freeze-thaw cycles of small working aliquots.