Anti-NFKBID Antibody

NFKBID (also known as IκBNS or IκB-delta) is the smallest member of the atypical IκB protein family and an inducible regulator of NF-κB transcriptional output in immune cells. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against endogenous human NFKBID and is supplied in a 200 µL vial, ready for pairing with the secondary detection system of choice.

The antibody is validated for Western blot and immunohistochemistry across human, mouse, and rat samples, supporting studies of NF-κB signaling in CD4+ and CD8+ T cells, B cells, macrophages, and lung epithelium. Because NFKBID is induced downstream of TCR engagement, LPS stimulation, CD40, and IL-10 signaling, and because it cooperates with p50 and c-Rel to regulate IL-2, IL-6, and Foxp3 expression, the reagent is well matched to investigations of T-helper17 differentiation, thymic Treg development, follicular helper T cell programming, and inflammatory gene programs.

The polyclonal format recognizes multiple epitopes across the target, which is helpful when probing NFKBID across species or in tissues with limited reagent coverage. Store at -20°C and avoid repeated freeze-thaw cycles; the product is intended for research use only and is not validated for diagnostic or therapeutic applications.