Anti-NFkB-p65 (M270) Antibody

Raised in rabbit against the NFkB-p65 transcription factor subunit (also known as RelA), this polyclonal antibody targets an epitope in the vicinity of residue M270 within the N-terminal Rel homology domain that mediates DNA binding and dimerization. The unconjugated reagent from Antibodies.com is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide, pH approximately 7.2, and is packaged as a 100 µl vial, providing ample reagent for multiple Western blot, immunohistochemistry, and immunoprecipitation experiments. Validated reactivity spans human, mouse, and rat samples, supporting studies of canonical NF-κB pathway activation in inflammation, immune signaling, and cellular stress models. Store refrigerated at 4°C to preserve activity; the sodium azide component serves as a microbial preservative. This reagent is intended for research use only.