Anti-NFkB-p105 (Ab-907) Antibody

Raised in rabbit against a synthetic peptide epitope surrounding residue 907 of the human NFkB-p105 precursor, this unconjugated polyclonal antibody from Antibodies.com selectively recognizes the full-length p105 protein and its processed p50 subunit. The target sits at the heart of the canonical NF-kB transcription factor signaling pathway, which governs inflammatory and immune responses, so the reagent is well matched to studies of cytokine-driven activation, IκB-mediated cytoplasmic retention, and nuclear translocation events in human cells and tissues.

Validated for Western blot and immunohistochemistry, the antibody is supplied as 100 µl of affinity-purified serum in a vial, ready for dilution into standard blotting and staining protocols. Researchers tracking stimulus-dependent p105 processing to p50, or comparing expression across patient-derived tissue sections, use it to map pathway activity in cell culture models and archival specimens. The unconjugated format also supports downstream pairing with HRP-, biotin-, or fluorophore-conjugated secondary reagents for chromogenic or immunofluorescence detection workflows.