Anti-NFkB-p105 (Ab-893) Antibody

This rabbit polyclonal reagent from Antibodies.com specifically recognizes the NFkB-p105 subunit (encoded by NFKB1) at a defined epitope designated Ab-893, supporting investigation of precursor processing, IκB complex dynamics, and generation of the p50 transcription factor in Human samples. Supplied as 100 µl of unconjugated antiserum, it is validated for western blot and immunohistochemistry workflows applied to cultured cell lysates and fixed tissue sections. Polyclonal reactivity broadens epitope coverage, which is advantageous when probing post-translational modifications or conformational variants of the p105 precursor that monoclonal reagents may miss. The unconjugated format permits flexible pairing with user-selected reporter labels, including HRP, biotin, Alexa Fluor, or alkaline phosphatase conjugates, for chromogenic, fluorescence, or chemiluminescent readout. Intended for research use only in studies of NFkB transcriptional activation, inflammatory cytokine signaling, apoptotic crosstalk, and innate immune pathway regulation within Human cellular and tissue model systems.