Anti-NFkB-p100 (S865) Antibody

This rabbit polyclonal IgG antibody specifically detects NFkB-p100 phosphorylated at serine 865, a modification linked to non-canonical NFkB pathway activation and processing of the p100 precursor into p52. Prepared by Antibodies.com, it is supplied at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide, pH approximately 7.2, in a 50 µl vial.

Validated for western blot, immunohistochemistry, and immunoprecipitation, the reagent recognizes human, mouse, and rat targets, supporting investigation of NFkB signaling in inflammatory, oncogenic, and immune regulatory contexts. The unconjugated format enables flexible labeling with HRP, fluorophore, or biotin secondary reagents for custom detection workflows. Store refrigerated to preserve activity across multiple freeze-thaw cycles when aliquoted from the stock.

Used in studies of p100 processing, RelB complex formation, and stimulus-dependent pathway engagement in cell lysates and tissue sections.