Anti-NFE2L1 Antibody

The Antibodies.com polyclonal reagent targets NFE2L1 (Nuclear Factor Erythroid 2-Like 1), also known as Nrf1, TCF11, or LCR-F1, an endoplasmic reticulum–resident transcription factor that orchestrates antioxidant response element (ARE) signaling and drives expression of proteasome subunit genes during oxidative and proteotoxic stress.

Raised in rabbits and supplied as an affinity-purified IgG polyclonal, this unconjugated preparation is validated for western blot and immunohistochemistry workflows against human and mouse targets. Investigators working on Nrf1-dependent proteostasis, ER-associated degradation, hematopoiesis, or neurodegenerative disease models can deploy this reagent to track protein expression and tissue localization across 50 µl of antibody per vial.

Storage at -20°C in working aliquots preserves polyclonal activity across limited freeze-thaw cycles, and the unconjugated format accommodates flexible pairing with secondary antibodies for chromogenic, HRP, or fluorescence-based detection in immunoblotting and immunostaining protocols.