Anti-NFE2L1 Antibody

This polyclonal antibody from Antibodies.com is raised in rabbit against NFE2L1 (Nuclear Factor, Erythroid 2-Like 1), also referred to in the literature as NRF1. The target is a Cap'n'Collar basic leucine zipper transcription factor that activates antioxidant response element (ARE)-driven gene programs and contributes to proteasome bounce-back under oxidative and proteotoxic stress. The reagent is unconjugated, of the IgG isotype, and supplied as a 200 µl working stock suitable for western blot and immunohistochemistry workflows on human and mouse samples. For best results, store at -20 °C in single-use aliquots to limit freeze-thaw cycles, and pair with HRP- or fluorophore-conjugated secondary reagents depending on whether chromogenic or immunofluorescence readout is required. Researchers studying redox homeostasis, ER stress, ER-associated degradation, and NRF1-dependent transcriptional regulation use this antibody on cell culture lysates and on paraffin or frozen tissue sections to probe endogenous NFE2L1 abundance and subcellular localization.