Anti-NFATC2 Antibody

Raised in rabbits and validated specifically for Western blot, this unconjugated polyclonal reagent targets Nuclear Factor of Activated T Cells 2 (NFATC2), a calcium-regulated transcription factor central to T lymphocyte signaling and inducible cytokine gene regulation. The antibody recognizes epitopes conserved across human, mouse, and rat NFATC2, supporting comparative immunoblotting studies in cell lysates and tissue homogenates. NFATC2 undergoes calcineurin-mediated dephosphorylation and nuclear translocation after T cell receptor engagement, making the protein a frequent marker in research on lymphocyte activation cascades, transplant tolerance models, autoimmune disease mechanisms, chondrogenesis, cardiac hypertrophy, and the transcription factor's emerging contribution to tumor microenvironment biology.

Supplied at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol, the 100 µl volume can be diluted directly into blocking buffer for routine immunoblotting protocols. Storage at -20 °C in single-use aliquots preserves activity across repeated experiments, and the glycerol formulation protects against incidental freeze-thaw. Each preparation is quality-controlled by Antibodies.com to deliver reproducible band detection in NFAT pathway studies.