Anti-NF2/Merlin Antibody

The polyclonal NF2/Merlin antibody from Antibodies.com is raised in rabbit and detects the endogenous tumor suppressor protein in human, mouse, and rat samples. NF2 gene mutations are linked to neurofibromatosis type 2 and to sporadic schwannomas, meningiomas, and ependymomas, making reliable immunodetection essential for nervous system tumor research and studies of Hippo pathway signaling, cytoskeletal-membrane linkages, and contact-dependent growth inhibition.

Supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated reagent in vial format supports flexible secondary labeling strategies for western blot, immunohistochemistry, and immunofluorescence workflows. The polyclonal nature provides recognition of multiple epitopes on Merlin, which is useful for tracking full-length expression, isoform variants, and truncated mutant forms in cell lysates and tissue sections.

Aliquot upon receipt and store refrigerated at 4 °C; avoid repeated freeze-thaw cycles to preserve antibody activity across multiple experiments.