Anti-NFκB-p65 Antibody

Produced in rabbits, this unconjugated polyclonal antibody targets the p65 (RelA) subunit of NF-κB, a transcription factor central to inflammatory gene expression and innate-immune signaling. The reagent is validated for Western blot, immunohistochemistry, and ELISA work on human, mouse, rat, and monkey samples, making it a flexible option for tracking canonical NF-κB pathway activation across cell- and tissue-based systems.

Supplied as a 50 µl aliquot from Antibodies.com, the antibody performs well with whole-cell lysates, cytoplasmic/nuclear fractionation preps, and fixed tissue sections, supporting common readouts such as phosphorylation shifts, IκBα degradation, and nuclear translocation following TNF-α, LPS, or cytokine challenge. Researchers studying inflammation, cancer biology, neurodegeneration, and host-pathogen responses routinely rely on p65 reagents like this one to map pathway engagement at the protein level.