Anti-NFκB-p105 Antibody

This rabbit polyclonal reagent from Antibodies.com targets the NFκB-p105 precursor encoded by the NFKB1 gene, allowing researchers to track both the unprocessed cytoplasmic form and its processing into the p50 DNA-binding subunit. Supplied as 100 µl of unconjugated antiserum, the antibody is validated for western blot, immunohistochemistry, immunoprecipitation, and ELISA against human samples, and is suited to studies of canonical NFκB signaling in inflammation, lymphocyte activation, and cellular stress responses.

The polyclonal format increases the likelihood of recognizing multiple epitopes across the p105 sequence, which is useful when monitoring proteolytic processing or comparing precursor-to-product ratios by immunoblotting. Because the reagent is unconjugated, it can be paired with user-selected HRP, biotin, or fluorophore-conjugated secondary antibodies, supporting downstream applications such as immunofluorescence on fixed cells or chromatin-related pull-down assays where p105/NFKB1 interactions are of interest. The product is intended for research use only and is supplied in a liquid vial format ready for dilution into standard blocking and wash buffers.