Anti-Neutrophil Cytosol Factor 1 (Ab-304) Antibody

This polyclonal antibody from Antibodies.com targets Neutrophil Cytosol Factor 1 (NCF1), the 47 kDa cytosolic organizer subunit of the phagocyte NADPH oxidase complex. The immunogen corresponds to a region surrounding residue 304 of the human protein, hence the Ab-304 designation, allowing selective detection of full-length NCF1/p47phox in cell lysates and tissue sections.

Raised in rabbit and supplied as 100 µl of unconjugated antiserum, the reagent is validated for Western blot (WB) and immunofluorescence (IF) workflows on human samples. Researchers commonly apply it to studies of oxidative burst, superoxide generation, and chronic granulomatous disease (CGD), since loss-of-function mutations in NCF1 cause autosomal recessive CGD type 1 with impaired respiratory burst in neutrophils.

The product ships as a single-use vial and is quality controlled for use in the listed applications.