Anti-Neurotensin Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets endogenous neurotensin (NTS), a 13-amino-acid peptide that functions both as a gastrointestinal hormone and as a neuromodulator in the central nervous system. Supplied as a 100 µl liquid aliquot in a single vial, it is validated for Western blot (WB) and ELISA workflows and shows reactivity with human, mouse, and rat samples, supporting use across translational neuroscience, gut-brain-axis, and metabolic research.

Neurotensin is best known for modulating dopaminergic signaling, nociception, thermoregulation, and feeding behavior, and altered NTS expression has been reported in the context of schizophrenia, Parkinson's disease, and certain gastrointestinal and pancreatic tumors. Because the reagent is unconjugated, it can be paired with HRP-, biotin-, or fluorophore-labeled secondary antibodies depending on the readout. Recommended handling is to aliquot upon receipt and store frozen at -20 °C, avoiding repeated freeze-thaw cycles; the product is intended for research use only and for in vitro laboratory applications.

Practical notes for end-users: for Western blot, a typical starting loading is 10-30 µg of total protein separated on SDS-PAGE and transferred to PVDF or nitrocellulose before probing; for ELISA, coat with the immunizing peptide at the concentration matched to the standard curve. Lot-specific titer and recommended starting dilution are provided on the data sheet shipped with each vial, and polyclonal bleed-to-bleed variation should be expected.