Anti-Netrin receptor DCC Antibody

The Antibodies.com polyclonal antibody to Netrin receptor DCC (Deleted in Colorectal Cancer) recognizes the ~160 kDa transmembrane receptor that mediates axon guidance cues during neural development and acts as a dependence receptor triggering apoptosis when unbound by netrin-1. Raised in rabbits and affinity-purified, this unconjugated IgG reagent is supplied as a 100 µg liquid aliquot in a single vial, validated for western blot detection of endogenous DCC in Human and Mouse samples. For best results, store the antibody frozen at -20°C in working aliquots to limit freeze-thaw cycles, and dilute in blocking buffer according to your optimized western blot protocol. The DCC receptor is widely studied in colorectal cancer research, neurodevelopmental biology, and netrin signaling pathways, where its expression status influences cell migration, axon pathfinding, and caspase-dependent cell death.