Anti-Nephrocystin-1 Antibody

Nephrocystin-1 (NPHP1) is a ciliary and centrosomal protein encoded by the NPHP1 gene, best known for its involvement in autosomal recessive nephronophthisis type 1 and Senior-Løken syndrome, conditions characterized by cystic kidney disease and retinal degeneration. This rabbit polyclonal antibody from Antibodies.com is raised against Nephrocystin-1 and supplied as an unconjugated reagent at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a stabilizer. The 100 µl vial format is validated for Western blot, immunohistochemistry, and immunofluorescence applications, and the antibody has been confirmed to react with human, mouse, and rat samples, supporting work across a range of experimental systems.

Researchers investigating ciliopathies, renal tubular biology, or photoreceptor degeneration can use this reagent to probe NPHP1 expression in tissue sections and cell preparations. Aliquot upon receipt if the vial will be opened multiple times, store refrigerated, and avoid repeated freeze-thaw cycles to preserve activity. For research use only.