Anti-Nephrocystin-1 Antibody

Nephrocystin-1 is the protein product of the NPHP1 gene, a ciliary and adherens-junction component whose loss-of-function is the most common monogenic cause of nephronophthisis, an autosomal recessive cystic kidney disease that progresses to end-stage renal failure in adolescents and young adults. This polyclonal reagent from Antibodies.com was raised in rabbit and is supplied unconjugated in a 100 µl vial at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide at approximately pH 7.2. It is validated for Western blot detection of the human, mouse, and rat target, supporting research into ciliopathy biology, primary cilium signaling, retinal-renal syndromes such as Senior-Løken syndrome type 1, and Joubert syndrome type 4. For short-term use, keep refrigerated; for long-term storage, aliquot and freeze to preserve activity across repeated freeze-thaw cycles. For research use only.