Anti-NEDD9 Antibody

NEDD9 (also known as HEF1 or Cas-L) is a focal adhesion scaffolding protein that integrates signals from integrins and growth factor receptors to regulate cell adhesion, migration, and cytoskeletal dynamics. This rabbit polyclonal antibody from Antibodies.com recognizes the human NEDD9 protein and cross-reacts with mouse and rat orthologs, supporting studies in cancer cell signaling, metastasis research, and integrin pathway analysis.

Supplied as a 100 µl liquid aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated antibody is validated for Western blot, immunofluorescence, and immunohistochemistry. Researchers commonly apply it to investigate focal adhesion turnover, Cas family signaling, and NEDD9 phosphorylation events downstream of Src and FAK kinases in melanoma, glioblastoma, and breast carcinoma models.

For storage, aliquot and store at -20°C; avoid repeated freeze-thaw cycles. The PBS-based buffer with 50% glycerol helps preserve antibody activity during short-term storage at 4°C for several weeks. Protect from light during use to maintain fluorescence downstream of immunolabeling.

This reagent is intended for research use only and is not approved for diagnostic or therapeutic applications.