Anti-Nectin 1 Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated primary antibody targets Nectin 1, a calcium-independent immunoglobulin-like cell adhesion molecule of the nectin family that is also known as PVRL1 and CD111. The antibody recognizes the human, mouse, and rat orthologs, enabling cross-species studies of adherens junction formation, epithelial integrity, and herpes simplex virus entry-receptor biology. Supplied at 100 µl, the reagent is validated for Western blot and ELISA workflows and is used to detect endogenous Nectin 1 in lysates from cultured cells or tissue samples. Investigators apply it to map Nectin 1 expression in neuronal, epithelial, and tumor-derived systems, and to probe virus-receptor interactions relevant to HSV-1 and HSV-2 pathogenesis. The polyclonal format offers broader epitope coverage than monoclonal alternatives, which is useful when characterizing multiple isoforms or post-translationally modified variants of Nectin 1. Antibodies.com ships the antibody as a ready-to-use liquid; for long-term retention, store aliquots at -20 °C and avoid repeated freeze-thaw cycles to preserve binding activity.