Anti-NDUFS4 Antibody

The NDUFS4-targeting polyclonal reagent from Antibodies.com is a rabbit-derived immunoglobulin preparation supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as cryoprotectant. This unconjugated primary antibody binds the mitochondrial iron-sulfur subunit S4 of NADH-ubiquinone oxidoreductase (respiratory chain Complex I), supporting research into oxidative phosphorylation, mitochondrial bioenergetics, and disorders such as Leigh syndrome and other complex I deficiency conditions.

Validated for Western blot (WB) and immunohistochemistry (IHC), the antibody recognizes human, mouse, and rat NDUFS4, enabling cross-species studies in neuroscience, cardiac metabolism, and metabolic disease models. The 100 µl volume at 1 mg/ml supports multiple immunoblots and staining runs depending on dilution, and the glycerol-containing buffer permits storage at -20°C with minimal freeze-thaw damage to the immunoglobulin. Researchers examining complex I assembly, supercomplex formation, or reactive oxygen species generation in neural and cardiac tissue will find the broad host reactivity (Human, Mouse, Rat) especially useful for comparing patient-derived samples to rodent model systems within a single workflow.