Anti-NDUFS2 Antibody

Raised in rabbit and purified by antigen affinity chromatography, this polyclonal reagent from Antibodies.com is directed against NDUFS2, the 49 kDa iron-sulfur subunit of mitochondrial complex I (NADH dehydrogenase, ubiquinone Fe-S protein 2). The immunogen is a synthetic peptide corresponding to an internal region of the human protein, and the antibody recognizes endogenous levels of total NDUFS2 in samples from human, mouse, and rat. It is supplied unconjugated at a concentration of 2.1 mg/mL in 100 µL of PBS (pH 7.3) containing 0.05% sodium azide and 50% glycerol, and is validated for Western blotting and immunohistochemistry on paraffin-embedded sections, where it stains, for example, human thyroid cancer tissue. The product is shipped at 4°C; on receipt it should be aliquoted and stored at −20°C, with repeated freeze/thaw cycles avoided to preserve activity. For research use only, this Antibodies.com primary antibody offers a reliable tool for studying mitochondrial respiratory chain assembly and oxidative phosphorylation complex I integrity across multiple species.