Anti-NDUFS1 Antibody

NDUFS1 is the largest and most catalytically critical subunit of mitochondrial respiratory Complex I (NADH:ubiquinone oxidoreductase), housing the flavin mononucleotide cofactor and the primary NADH oxidation site. This rabbit polyclonal antibody from Antibodies.com is raised against NDUFS1 and supplied as an unconjugated, 100 µl aliquot suitable for western blot and immunohistochemistry workflows in human, mouse, and rat samples.

Researchers studying mitochondrial bioenergetics, oxidative phosphorylation, and the molecular basis of disorders such as Leigh syndrome use this reagent to track Complex I assembly, steady-state subunit levels, and tissue-specific expression patterns in neural, cardiac, and skeletal muscle contexts. The polyclonal format provides multi-epitope recognition of the ~75 kDa NDUFS1 protein, supporting detection of full-length and partially processed forms under reducing SDS-PAGE conditions.

For short-term use, keep the vial refrigerated; for longer-term storage, aliquot and freeze at -20 °C to limit freeze-thaw degradation of the immunoglobulin. The host species is rabbit and the reagent is supplied without a fluorophore or enzyme conjugate, giving users full flexibility to pair it with HRP-, biotin-, or Alexa Fluor-labelled secondary antibodies of their choice. For research use only.