Anti-NDUFS1 Antibody

Mitochondrial Complex I research often requires specific detection of the NDUFS1 subunit (NADH-ubiquinone oxidoreductase 75 kDa subunit), the largest core component of this respiratory chain complex. This rabbit polyclonal reagent from Antibodies.com supports targeted detection of NDUFS1 in Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows.

Validated for reactivity against human, mouse, and rat samples, the unconjugated format gives researchers flexibility to pair it with HRP, fluorophore, or biotin-labeled secondary reagents depending on assay needs. Each vial contains 100 µl of polyclonal antiserum raised in rabbit, suitable for semi-quantitative immunoblotting and tissue-localization studies exploring oxidative phosphorylation, mitochondrial bioenergetics, and Complex I deficiency models such as Leigh syndrome.

Researchers investigating neurodegeneration, metabolic disease, or mitochondrial dysfunction can use this reagent with cell culture-derived lysates, frozen tissue sections, and fixed cell preparations. Refrigerated storage is recommended to preserve antibody activity, and aliquoting is advised to limit freeze-thaw cycles.