Anti-NDUFB10 Antibody

NDUFB10 is a small accessory subunit of mitochondrial Complex I (NADH:ubiquinone oxidoreductase), the first enzyme of the electron transport chain, where it contributes to the assembly and stability of the NADH dehydrogenase module. This unconjugated rabbit polyclonal antibody from Antibodies.com was raised against the human NDUFB10 protein and is supplied as 100 µl of polyclonal antiserum for use in western blot and immunohistochemistry workflows.

The reagent is reactive with human samples and is unconjugated, allowing researchers to pair it with custom detection chemistries, secondary antibodies of their choice, or quantitative fluorescent readouts. The polyclonal format provides recognition of multiple epitopes on NDUFB10, which is useful when probing low-abundance targets, partially denatured lysates, or subtle changes in expression that may accompany Complex I deficiency.

Typical applications include characterizing NDUFB10 levels in patient-derived cells, tissue sections, and disease models linked to mitochondrial dysfunction, oxidative phosphorylation disorders, and neurodegeneration. The antibody also supports studies of respiratory chain assembly, mitochondrial biogenesis, and the cellular response to metabolic or oxidative stress. Storage at 4 °C is recommended for short term use, with aliquoting advised to limit freeze-thaw cycles and preserve reagent performance across repeated experiments.