Anti-NDUFA4L2 Antibody

Raised in rabbit, this unconjugated polyclonal antibody recognizes NDUFA4L2, a mitochondrial complex I accessory subunit whose expression is upregulated under low-oxygen conditions through HIF-1α-dependent transcription. Useful for probing hypoxic adaptation in cell culture and tissue models, the reagent cross-reacts with both human and mouse orthologues and has been validated for western blot and ELISA workflows. Each vial contains 100 µl of liquid antiserum, supplied as an unconjugated preparation that can be conjugated or directly labelled to fit downstream detection chemistries. Investigators studying clear-cell renal carcinoma, ischemic tissue injury, or mitochondrial remodeling under hypoxia have used anti-NDUFA4L2 antibodies from Antibodies.com to track complex I composition changes in mitochondrial fractions and whole-cell lysates.