Anti-NDUFA1 Antibody

Mitochondrial Complex I (NADH dehydrogenase) research depends on subunit-specific detection reagents, and the unconjugated rabbit polyclonal antibody from Antibodies.com is raised against NDUFA1, an X-linked accessory subunit required for proper Complex I assembly and electron transport function. Mutations in NDUFA1 have been associated with Leigh syndrome and other mitochondrial disorders, making reliable detection tools valuable for studies of oxidative phosphorylation and neurodegeneration.

Each vial contains 100 µl of polyclonal antiserum validated for western blot (WB) and immunohistochemistry (IHC) applications on human samples. The polyclonal format enables recognition of multiple epitopes on the NDUFA1 protein, which can improve signal robustness across western blot experiments and IHC staining of tissue sections. The reagent is unconjugated, allowing researchers to pair it with secondary antibodies of their choice for flexible assay design.

This reagent is reactive with human NDUFA1 and is intended for research use only in studies of mitochondrial dysfunction, complex I deficiency, metabolic disease mechanisms, and related neuroscience investigations. Applications include protein expression profiling, subcellular localization studies in fixed tissue, and confirmation of NDUFA1 levels in patient-derived cell lines.