Anti-NDRG4 Antibody

This rabbit polyclonal primary antibody targets NDRG4 (N-Myc Downstream Regulated Gene 4), a member of the NDRG family predominantly expressed in brain and heart tissue. NDRG4 has been investigated in neuronal differentiation and stress response studies, and methylated NDRG4 has been examined as a stool-DNA biomarker for colorectal cancer research. The reagent is supplied unconjugated at 50 µl per vial, supporting standard immunodetection workflows.

Validated for Western blot and immunohistochemistry, this unconjugated IgG antibody cross-reacts with human, mouse, and rat NDRG4, making it applicable to comparative studies across these species. The polyclonal format increases the likelihood of detecting endogenous NDRG4 isoforms in tissue lysates and fixed sections, since multiple epitopes are recognised. Researchers pair the unconjugated primary with HRP- or fluorophore-conjugated secondary reagents of their choice. Aliquot on receipt and store frozen to limit freeze-thaw cycles of the antibody solution.

From Antibodies.com, the polyclonal reagent serves laboratories investigating NDRG4 function in neural development, cardiomyocyte biology, or tumor biology, where broad epitope recognition is helpful when probing endogenous protein levels.