Anti-NDRG1 Antibody

Raised in rabbit against the NDRG1 stress-response protein, this polyclonal antibody from Antibodies.com is supplied as a 100 µl vial of unconjugated antiserum at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol for liquid-state stability. NDRG1 (N-Myc Downstream Regulated 1) is widely studied in cellular stress, hypoxia signaling, and tumor progression, where it acts as a downstream effector of HIF-1α and is implicated in metastasis suppression across several cancer models. Researchers apply the reagent for western blot detection of the approximately 43 kDa NDRG1 band in Human, Mouse, and Rat lysates, for immunohistochemistry localization in tissue sections, and for immunofluorescence imaging of subcellular distribution under stress conditions. The polyclonal format offers broader epitope coverage than monoclonal alternatives, useful when probing isoforms or post-translationally modified forms. Sodium azide in the buffer prohibits live-cell labeling work and azide-sensitive conjugation reactions, so users should dialyze or buffer-exchange before such protocols. Store refrigerated in working aliquots to minimize freeze-thaw cycles of the glycerol stock, and protect from light to preserve antibody integrity for repeated experimental runs.