Anti-NDP Antibody

The NDP gene encodes Norrin (Norrie Disease Protein), a secreted cysteine-knot signaling molecule that activates the Wnt/β-catenin pathway by binding the FZD4 and LRP5/6 receptor complex on target cells. This rabbit polyclonal antibody from Antibodies.com is raised against Norrin and validated for Western blot and immunohistochemistry. Each 100 µl aliquot is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotective stabilizer. Reactivity has been confirmed on human, mouse, and rat samples, supporting research into retinal vasculature development, Norrie disease pathogenesis, and FZD4-associated ophthalmologic and vascular models.