Anti-NDC80 Antibody

This rabbit polyclonal antibody targets NDC80 (also known as Hec1), a core component of the NDC80 kinetochore complex that mediates chromosome alignment and microtubule attachment during mitosis. Manufactured by Antibodies.com as a Primary Antibody reagent, it is raised in rabbit and supplied unconjugated in a 100 µl vial. Validated applications include Western blot (WB) and immunohistochemistry (IHC), with confirmed reactivity against human, mouse, and rat samples. NDC80 is widely studied in cell division and cancer research owing to its essential role at the kinetochore-microtubule interface and its frequent overexpression in tumors, where altered levels correlate with chromosomal instability and poor prognosis. The unconjugated format allows flexibility for downstream conjugation with fluorophores, biotin, or HRP to suit varied experimental workflows. Recommended storage is refrigerated; small aliquots help preserve antibody activity across repeated freeze-thaw cycles. For research use only.