Anti-NCSTN Antibody

Offered through the Antibodies.com catalogue, this rabbit polyclonal reagent is raised against nicastrin (NCSTN), also known by the synonyms APH2 and KIAA0253, a subunit of the gamma-secretase complex that has been investigated in the context of Alzheimer's disease and Notch signalling. The antibody is supplied as an unconjugated IgG preparation at 1 mg/mL in a storage buffer of PBS containing 0.1% sodium azide and 50% glycerol, and is provided in a 50 µL vial. It has been validated for Western blot (WB) and immunohistochemistry (IHC) applications, and the manufacturer states an estimated purity greater than 95% following affinity purification against the immunogen. The host species is rabbit, the clonality is polyclonal, the conjugate is unconjugated, and the isotype is IgG. Cross-reactivity has been confirmed in human, mouse and rat samples, making the reagent suitable for translational studies that compare nicastrin expression between rodent models and human tissue. As with most primary antibodies in this supplier's range, the preparation is intended for research use only and should be stored according to the cold-chain recommendations on the accompanying datasheet to preserve activity of the 1 mg/mL stock.