Anti-NCR1 Antibody

NCR1, also known as NKp46 and CD335, is a type I transmembrane glycoprotein belonging to the natural cytotoxicity receptor family. It is expressed almost exclusively on resting and activated natural killer (NK) cells, where it functions as a triggering receptor that mediates lysis of tumor cells and virus-infected cells. This Rabbit polyclonal antibody from Antibodies.com targets the human NCR1 protein for detection in research applications.

Validated for western blot and immunofluorescence workflows, the unconjugated reagent is supplied as 100 µl of polyclonal antiserum raised in Rabbit. The antibody recognizes the native human receptor and is suited to studies of NK cell biology, innate immunity, tumor immunology, and antiviral responses. Brief storage at -20 °C in working aliquots preserves reagent activity and limits freeze-thaw damage to the immunoglobulin preparation.

For western blot, sample lysates are resolved by SDS-PAGE and probed with the antibody at empirically determined dilutions. For immunofluorescence, the reagent can be applied to fixed cell preparations or tissue sections to localize NCR1-positive NK cells within mixed populations.