Anti-NCOR2 Antibody

NCOR2 (Nuclear Receptor Corepressor 2, also known as SMRT) is a large nuclear protein that partners with histone deacetylase complexes to silence thyroid hormone, retinoic acid, and other nuclear receptor target genes in the absence of ligand. This rabbit polyclonal antibody from Antibodies.com targets a region of human NCOR2 and is supplied as 100 µl of unconjugated serum, suitable for Western blot and immunohistochemistry workflows on human samples.

As a polyclonal reagent, the antibody recognizes multiple epitopes across the NCOR2 protein, which helps when probing the full-length ~270 kDa corepressor in chromatin and transcription factor studies. Recommended storage is at -20°C in small aliquots to limit freeze-thaw cycles, and the unconjugated format lets researchers pair it with HRP, fluorophore, or biotin secondary antibodies of their choice for chromogenic or immunofluorescence detection.

Validated uses include Western blot detection of NCOR2 in nuclear extracts and IHC localization in formaldehyde-fixed paraffin-embedded tissue sections from human sources.