Anti-NCOA4 Antibody

Raised in Rabbit as a polyclonal IgG reagent, this unconjugated primary antibody from antibodies.com targets NCOA4 (Nuclear Receptor Coactivator 4), a protein with two distinct biological roles: it acts as a transcriptional coactivator of the androgen receptor, and more recently it has been identified as the selective cargo receptor that drives ferritinophagy, the autophagic degradation of ferritin that releases free intracellular iron. The reagent is supplied at 100 µl per vial and is validated for Western blot and immunohistochemistry applications across human, mouse, and rat samples, making it well suited for research on androgen-driven transcription, iron homeostasis, and ferroptosis in cancer and metabolic disease models.

Supplied unconjugated, the antibody integrates cleanly with HRP- or fluorophore-conjugated secondaries chosen by the researcher for chemiluminescent WB or chromogenic IHC detection. The polyclonal IgG format generally recognises multiple epitopes along conserved regions of NCOA4, which is useful when probing both full-length NCOA4 and shorter isoforms such as NCOA4α and NCOA4β. Aliquoting upon first use and storage at standard short-term antibody conditions preserves titre across longer projects.