Anti-NCL Antibody

This polyclonal primary antibody from Antibodies.com targets nucleolin (NCL), a highly abundant nucleolar phosphoprotein that plays a central role in ribosome biogenesis, rDNA transcription, and RNA processing. Produced in rabbit and validated for both Western blot and immunohistochemistry, the reagent binds endogenous NCL in human and mouse samples, supporting studies of nucleolar architecture, cell proliferation, and stress responses. The unconjugated IgG is supplied as 100 µl of a 1 mg/ml stock in PBS containing 0.1% sodium azide and 50% glycerol, and is intended to be stored frozen at -20°C in single-use aliquots to minimize freeze-thaw cycles. Researchers investigating cancer biology, ribosomal RNA processing, or viral host factor interactions frequently use anti-NCL antibodies to map nucleolar localization and track changes in nucleolin expression during differentiation or oncogenic transformation.