Anti-NCK1 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets NCK1, a non-catalytic SH2/SH3 adaptor protein that couples activated receptor tyrosine kinases to downstream effectors controlling actin cytoskeleton remodeling and cell migration. The reagent is supplied as 100 µl of polyclonal antiserum in a single vial and is validated for Western blot (WB) and immunohistochemistry (IHC) on human samples, making it a practical tool for studying NCK1 expression in tumor biology and signal transduction research where melanoma, breast cancer, and receptor tyrosine kinase pathways are under investigation.

Because the antibody is unconjugated and polyclonal, it offers flexibility for researchers who want to pair it with custom secondary labels or amplification systems. The host species is rabbit, and the reagent is intended for research use only in immunoblotting of cell lysates and tissue section staining workflows that probe adaptor-protein involvement in cytoskeletal regulation and downstream kinase cascades such as PAK, N-WASP, and Rac1 activation.