Anti-NCAN Antibody

This polyclonal antibody targets Neurocan (NCAN), a chondroitin sulfate proteoglycan and member of the hyalectican family that is abundantly expressed in the central nervous system. Raised in rabbit and supplied as an unconjugated IgG preparation at 50 µl per vial, the reagent is validated for western blot and immunohistochemistry workflows in human, mouse, and rat samples. Neurocan is a key structural component of the brain extracellular matrix and contributes to perineuronal net assembly, synaptic maturation, and experience-dependent plasticity, making this antibody useful for studies of neural development, glial scarring following central nervous system injury, and extracellular matrix remodeling in neurodegenerative models. The unconjugated format allows flexible pairing with secondary antibodies labeled to the user's preferred fluorophore or enzyme. Antibodies.com lists this reagent within its Primary Antibodies portfolio for neuroscience and matrix biology research.