Anti-NAP1L1 Antibody

NAP1L1 (Nucleosome Assembly Protein 1-Like 1) functions as a histone chaperone that drives nucleosome assembly and disassembly, with documented roles in cell cycle progression, transcription regulation, chromatin remodeling, and neuronal differentiation. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against the NAP1L1 target and validated for Western blot (WB) and immunohistochemistry (IHC).

Reactivity is confirmed against human, mouse, and rat samples, supporting comparative work across these model systems in cell biology, oncology, and neuroscience research. Published studies have reported elevated NAP1L1 expression in hepatocellular carcinoma and other tumor types, and have used this reagent to explore interactions with cell cycle partners such as cyclin B1 during G2/M transition, as well as roles in neural progenitor cell fate decisions.

The antibody is supplied as 100 µl of liquid. For best stability, it should be aliquoted and stored at -20 °C, with freeze-thaw cycles minimized. In Western blot, NAP1L1 is typically detected at an apparent molecular weight near 45-55 kDa. For IHC, the antibody can be applied to formalin-fixed paraffin-embedded tissue sections. The polyclonal format allows recognition of multiple epitopes on the target, increasing robustness across varied experimental conditions.