Anti-NAMPT Antibody

This polyclonal antibody from Antibodies.com targets nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in the NAD+ salvage pathway that converts nicotinamide to nicotinamide mononucleotide. Raised in rabbit, the unconjugated reagent is supplied as 100 µl of antiserum validated for Western blot, immunohistochemistry, and immunofluorescence workflows. It cross-reacts with NAMPT from human, mouse, and rat origin, supporting translational studies in cultured mammalian cells and tissue sections.

NAMPT, also known as visfatin or PBEF, has attracted sustained interest in metabolic and oncological research, where its expression in cytoplasm, nucleus, and extracellular compartments has been linked to insulin signaling, inflammatory responses, and tumor cell survival. Researchers therefore deploy this reagent to probe NAD biosynthesis, stress-induced metabolic adaptation, and immune cell function in basic and preclinical settings. For best results, refrigerate the vial in working aliquots to limit freeze-thaw cycles and preserve binding activity over the shelf life of the reagent.