Anti-Na+ CP type IXα (R692) Antibody

Raised in rabbit and affinity-purified by epitope-specific immunogen chromatography, this polyclonal reagent from Antibodies.com targets the intracellular R692 region of the voltage-gated sodium channel Na+ CP type IXα, also known as Nav1.7 or SCN9A. The immunogen corresponds to a synthetic peptide derived from amino acids 660–718 of the human protein, and the antibody is reported to detect endogenous levels of the target. Supplied as a 50 µl liquid at approximately 1 mg/ml in phosphate-buffered saline (PBS) containing 0.05% sodium azide at roughly pH 7.2, the product is unconjugated and of the IgG isotype, making it well suited to standard detection workflows. Validated applications include Western blot (WB), typically used at 1:500–1:000, and immunohistochemistry (IHC), typically used at 1:50–1:200, and the reagent shows cross-reactivity with human, mouse and rat samples. For short-term storage the vial can be kept at 4 °C, while long-term it should be aliquoted and stored at –20 °C with freeze–thaw cycles avoided. Researchers studying nociception, dorsal root ganglion signalling, or the contribution of Nav1.7 to inherited pain disorders such as inherited erythromelalgia (IEM) will find this Antibodies.com reagent a reliable tool for probing channel expression and localisation across species.