Anti-MYSM1 Antibody

Raised in rabbit and supplied as an unconjugated polyclonal reagent, this antibody targets MYSM1, a metalloprotease that removes monoubiquitin from histone H2A and regulates transcription in hematopoietic and immune cell lineages. The 100 µl volume is validated for Western blot and immunohistochemistry on human and mouse samples, supporting studies in chromatin biology, B-cell development, and the DNA damage response where MYSM1 function is being investigated.

Researchers at Antibodies.com use this reagent to track endogenous MYSM1 protein levels across differentiating blood cells and to probe its role in maintaining hematopoietic stem cell pools, where loss of MYSM1 has been linked to defective lymphocyte maturation and impaired DNA repair signaling.