Anti-MYOZ2 Antibody

This rabbit polyclonal antibody targets MYOZ2 (Myozenin 2), a sarcomeric Z-disc protein also known as calsarcin-1 that anchors calcineurin to the contractile apparatus of striated muscle. Provided by Antibodies.com as an unconjugated primary antibody in a 100 µl volume, it is validated for Western blot (WB) and immunofluorescence (IF) applications on human samples, supporting studies of cardiac and skeletal muscle differentiation, sarcomere assembly, and Z-disc signaling.

MYOZ2 interacts with alpha-actinin at the Z-line and has been implicated in hypertrophic cardiomyopathy and muscle-specific gene regulation. The polyclonal format offers broad epitope coverage, which is useful when probing endogenous MYOZ2 expression across multiple tissue lysates or when characterizing patient-derived samples by immunofluorescence staining of muscle fibers.

For Western blot, the antibody can be paired with standard HRP- or fluorophore-conjugated secondary reagents, and for IF, it is compatible with common fixation and permeabilization protocols used for cultured myocytes or skeletal muscle cryosections. The unconjugated format allows researchers to choose their own detection chemistry depending on the experimental design.