Anti-MYOZ2 Antibody

This polyclonal antibody from Antibodies.com targets MYOZ2 (Myozenin 2), a sarcomeric Z-disc protein that binds alpha-actinin and calcineurin in striated muscle. Produced in rabbit hosts and supplied as 100 µl of unconjugated IgG at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent is validated for Western blot, immunohistochemistry, and immunofluorescence applications on human tissues.

The glycerol-containing buffer keeps the antibody liquid at –20 °C, so users store the vial frozen and withdraw small aliquots to minimize freeze-thaw cycles of the parent stock. Because it is unconjugated, the antibody can be paired with any secondary reporter, used in immunoprecipitation, or applied directly to fixed sections and lysates. Species reactivity is reported for human, and the polyclonal backbone offers recognition of multiple epitopes on the Myozenin 2 protein, which is helpful when probing splice variants or post-translational modifications relevant to cardiac and skeletal muscle research.

MYOZ2, also known as calsarcin-1, is most strongly expressed in cardiac myocytes and fast-twitch skeletal muscle fibers, making this Antibodies.com reagent useful for studies of sarcomere organization, calcineurin signaling, and hypertrophic cardiomyopathy. Each lot is affinity-purified and quality-controlled in WB and IHC against human controls to confirm target specificity before release.