Anti-MYO1C Antibody

This polyclonal antibody from Antibodies.com targets MYO1C, a class I unconventional myosin broadly studied for its roles in actin-based membrane trafficking, insulin-stimulated GLUT4 vesicle translocation, and the regulation of RNA polymerase I and III transcription. Raised in rabbit and supplied at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% glycerol, the 100 µl vial is unconjugated, allowing flexibility for downstream labeling in custom detection workflows.

Validated for western blot, immunohistochemistry, and immunofluorescence, the reagent reacts with human, mouse, and rat samples, supporting cross-species studies in cell signaling, metabolic regulation, and cytoskeletal dynamics. MYO1C is implicated in glucose homeostasis, chromatin remodeling at the nuclear envelope, and cargo transport along actin filaments, making this antibody a practical tool for laboratories investigating membrane trafficking, insulin response pathways, or nuclear transcription mechanisms.

The polyclonal format offers recognition of multiple epitopes on the MYO1C protein, which is useful for detecting lower-abundance targets or partially denatured antigens in fixed tissue sections. For storage, the glycerol-containing buffer is compatible with aliquoting and storage at -20 °C, with minimal freeze-thaw damage when handled as working aliquots and protected from light during use.